3-METHYL-1,3-THIAZOLANE-2,4-DIONE
- Product Name
- 3-METHYL-1,3-THIAZOLANE-2,4-DIONE
- CAS No.
- 16312-21-3
- Chemical Name
- 3-METHYL-1,3-THIAZOLANE-2,4-DIONE
- Synonyms
- 2,4-Thiazolidinedione, 3-methyl-;3-METHYL-1,3-THIAZOLANE-2,4-DIONE;3-methyl-1,3-thiazolidine-2,4-dione
- CBNumber
- CB4244824
- Molecular Formula
- C4H5NO2S
- Formula Weight
- 131.15
- MOL File
- 16312-21-3.mol
3-METHYL-1,3-THIAZOLANE-2,4-DIONE Property
- Melting point:
- 40-43°C
- Boiling point:
- 130-131 °C(Press: 14 Torr)
- Density
- 1.421±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -2.27±0.20(Predicted)
Safety
- HazardClass
- IRRITANT
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
N-Bromosuccinimide Price
- Product number
- M331458
- Product name
- 3-Methylthiazolidine-2,4-dione
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR926563
- Product name
- 3-Methyl-1,3-thiazolane-2,4-dione
- Purity
- 95%
- Packaging
- 1g
- Price
- $225
- Updated
- 2021/12/16
- Product number
- 045402
- Product name
- 3-Methyl-1,3-thiazolane-2,4-dione
- Purity
- >95%
- Packaging
- 1g
- Price
- $228
- Updated
- 2021/12/16
- Product number
- OR926563
- Product name
- 3-Methyl-1,3-thiazolane-2,4-dione
- Purity
- 95%
- Packaging
- 250mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- 045402
- Product name
- 3-Methyl-1,3-thiazolane-2,4-dione
- Purity
- >95%
- Packaging
- 500mg
- Price
- $181
- Updated
- 2021/12/16
3-METHYL-1,3-THIAZOLANE-2,4-DIONE Chemical Properties,Usage,Production
Uses
3-methyl-1,3-thiazolidine-2,4-dione can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
To a solution of 2,4-thiazolidinedione (1 equiv) in 5 mL of DMF was added potassium carbonate (1.1 equiv) and halogen (1.1 equiv). The suspension was stirred at 80 oC overnight. Solvent was evaporated and the residue was purified by flash column chromatography ( petroleum ether/EtOAc, 5:1) to afford the product 3. 3-Methylthiazolidine-2,4-dione (3a) Following the previous procedure, 2,4-thiazolidinedione (500 mg, 4.3 mmol) and iodomethane (0.3 mL, 4.7 mmol). 3a as white solid (460 mg, 82%).